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Projects

Here, we present a list our central projects. Please visit the given links for more information about the respective projects.

 

BALLBALL_Logo

 

The Biochemical Algorithms Library (BALL) is a C++ framework for rapid software prototyping in Computational Molecular Biology and Molecular Modeling.

BN++BN++_Logo

The Biochemical Network library (BN++) is a comprehensive framework for modeling, analyzing, and visualizing biochemical pathways and networks.

CAPCAP_Logo

The 'Cancer-Associated Proteins' database (CAP) is an integrated tool for analysing proteins that show an altered expression in certain tumor types.

DockingDocking_Logo

The main goal of this project is the development of algorithms for predicting the 3D-structures of protein-protein complexes.

GeneTrailGeneTrail_Logo

We are developing a web-based application, called GeneTrail, that facilitates the statistical evaluation of comprehensive genomic and proteomic data sets with respect to the enrichment of biological categories.

Molecular

DiagnosisMolecularDiagnosis_Logo

 

Sets of autologous antigen possess high potential for non invasive molecular diagnosis and monitoring. We are developing a statistical framework to perform an accurate diagnosis of various dieseases based on autoantibody profiles.

SolvationSolvation_Logo

Since most biochemical processes require the presence of water, solvation effects play a major role that have to be modelled correctly in order to achieved reliable and meaningful binding energy and docking predictions. Therefore, we are developing improved continuum models for solvation.